How to Use the Morphine Drug ? Ailments and the Limits
What is morphine?
Morphine is an opioid torment pharmaceutical drug. An opioid is infrequently called an opiate. Morphine is utilized to treat moderate to serious torment. Short-acting details are taken as required for agony. The developed discharge type of this drug is for day and night treatment of torment. This type of morphine is not for use on an as-required premise for agony. Morphine is not for treating transient torment soon after surgery unless you were at that point taking morphine before the surgery.
Note that : Morphine may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
Abuse of NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, or DEATH, particularly in a kid or other individual utilizing the pharmaceutical without a solution.
Tell your doctor if you are pregnant.
Morphine may cause life-threatening withdrawal symptoms in a newborn .
You ought not take this pharmaceutical in the event that you have ever had an unfavorably susceptible response to morphine or other opiate meds, or on the off chance that you have:
serious asthma or breathing issues;
a blockage in your stomach or insides; or
a gut impediment called immobile ileus.
Try not to utilize morphine on the off chance that you have utilized a MAO inhibitor as a part of the previous 14 days. An unsafe medication cooperation could happen. MAO inhibitors incorporate isocarboxazid, linezolid, methylene blue infusion, phenelzine, rasagiline, selegiline, tranylcypromine, and others.
You will be unable to take morphine on the off chance that you are NOT as of now being treated with a comparative opioid (opiate) torment drug and are tolerant to it. Converse with your specialist in the event that you are not certain you are opioid-tolerant.
To ensure morphine is alright for you, tell your specialist in the event that you have:
any kind of breathing issue or lung sickness;
a past filled with head harm, mind tumor, or seizures;
a past filled with medication misuse, liquor dependence, or dysfunctional behavior;
pee issues;
liver or kidney sickness; or
issues with your gallbladder, pancreas, or thyroid.
It is not known whether this solution will hurt an unborn infant. In the event that you utilize morphine while you are pregnant, your infant could get to be subject to the medication. This can bring about existence debilitating withdrawal manifestations in the child after it is conceived. Babies conceived subject to propensity shaping drug might require medicinal treatment for a few weeks. Tell your specialist on the off chance that you are pregnant or plan to end up pregnant.
How To Use Morphine ?
Here comes the big question , how to use this drug ?
Take morphine precisely as recommended by your specialist. Take after all bearings on your remedy name. Morphine can moderate or stop your breathing, particularly when you begin utilizing this pharmaceutical or at whatever point you dosage is changed. Never take morphine in bigger sums, or for more than endorsed. Tell your specialist if the medication appears to quit filling in too in soothing your agony.
Continuously check your container to ensure you have gotten the right pills (same brand and sort) of solution endorsed by your specialist. Inquire as to whether you have any inquiries concerning the medication you get at the drug store. Quit taking all other day and night opiate torment drugs when you begin taking morphine.
Try not to squash, bite, or break an augmented discharge tablet. Gulp down it to keep away from introduction to a possibly deadly measurement.
To make gulping less demanding, you might open the Avinza or Kadian container and sprinkle the medication into a spoonful of fruit purée. Swallow immediately without biting. Try not to spare the blend for later utilize.
Measure fluid prescription with an extraordinary dosage measuring spoon or drug container, not with a normal table spoon. In the event that you don't have a measurements measuring gadget, approach your drug specialist for one.
Take the pharmaceutical in the meantime every day.
Try not to quit utilizing morphine all of a sudden, or you could have unsavory withdrawal side effects. Ask your specialist how to securely quit utilizing this drug.
Never pound or break a morphine pill to breathe in the powder or blend it into a fluid to infuse the medication into your vein. This practice has brought about death with the abuse of morphine and comparable doctor prescribed medications.
Store at room temperature, far from warmth, dampness, and light.
Monitor the measure of prescription utilized from each new container. Morphine is a medication of misuse and you ought to know whether anybody is utilizing your pharmaceutical despicably or without a solution.
Try not to keep remaining morphine pills or fluid. Request that your drug specialist where find a medication take-back transfer program. In the event that there is no take-back system, flush any unused pills or fluid down the latrine. Transfer of prescriptions by flushing is prescribed to diminish the peril of unintentional overdose bringing about death. This exhortation applies to a little number of solutions as it were. The FDA, working with the producer, has decided this strategy to be the most proper course of transfer and shows minimal danger to human security.
What If someone miss a dosage?
Morphine is once in a while taken just once every day, and at times 2 or 3 times each day. Since morphine is utilized for torment, you are not liable to miss a measurements. On the off chance that you do miss a measurements, take the pharmaceutical when you recollect. At that point take your next measurements as takes after:
On the off chance that you take morphine 3 times each day: Take your next measurements 8 hours subsequent to taking the missed dosage.
On the off chance that you take morphine 2 times each day: Take your next measurements 12 hours subsequent to taking the missed dosage.
On the off chance that you take morphine 1 time for each day: Take your next dosage 24 hours in the wake of taking the missed measurement.
Try not to take additional solution to make up a missed measurement. Try not to take more than your recommended dosage in a 24-hour period.
What If someone Overdose ?
Look for crisis restorative consideration or call the Poison Help line at 1-800-222-1222. A morphine overdose can be lethal, particularly in a tyke or other individual utilizing the pharmaceutical without a medicine. Overdose side effects might incorporate moderate breathing and heart rate, serious tiredness, muscle shortcoming, icy and damp skin, pinpoint students, and blacking out.
What Things to avoid ?
Try not to drink liquor (alcohol). Unsafe symptoms or demise can happen when liquor is joined with morphine. Check your sustenance and prescription marks to make sure these items don't contain liquor.
This pharmaceutical might disable your reasoning or responses. Abstain from driving or working apparatus until you know how morphine will influence you. Discombobulation or extreme tiredness can bring about falls or different mischances.
Side Effects of Morphine Drugs :
Morphine side effects
Get emergency medical help if you have signs of an allergic reaction to morphine: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- slow heart rate, sighing, weak or shallow breathing;
- chest pain, fast or pounding heartbeats; or
- extreme drowsiness, feeling like you might pass out.
Morphine is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.
Common morphine side effects may include:
- drowsiness, dizziness;
- constipation, stomach pain, nausea, vomiting;
- headache, tired feeling;
- anxiety; or
- mild itching.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Morphine dosing information
Usual Adult Dose of Morphine for Pain:
Oral, Sublingual, or Buccal: 5 to 30 mg every 3 to 4 hours as needed
Extended-release capsules:
Avinza (R) extended-release capsules and approved generics:
For use only in opioid tolerant patients:
To be taken orally once daily swallowed whole or opened and sprinkled on a small amount of applesauce immediately prior to ingestion.
Maximum dose: 1600 mg orally daily
Kadian (R) extended-release capsules and approved generics:
100 mg and 200 mg for use only in opioid tolerant patients:
To be taken orally 1 to 2 times daily swallowed whole or opened and sprinkled on a small amount of applesauce immediately prior to ingestion.
IM or subcutaneous: 2.5 to 20 mg every 3 to 4 hours as needed
IV: 4 to 15 mg every 3 to 4 hours as needed. Give very slowly over 4 to 5 minutes. Starting doses up to 15 mg every 4 hours have been used. Chest pain: 2 to 4 mg repeat as necessary
Continuous IV: 0.8 to 10 mg/hour. Maintenance dose: 0.8 to 80 mg/hour. Rates up to 440 mg/hour have been used.
IV patient controlled analgesia or subcutaneous patient controlled analgesia: 1 to 2 mg injected 30 minutes after a standard IV dose of 5 to 20 mg. The lockout period is 6 to 15 minutes. The 4 hour limit is 30 mg.
Continuous subcutaneous: 1 mg/hour after a standard dose of 5 to 20 mg
Epidural: 5 mg one time. May give 1 to 2 mg more after one hour to a maximum of 10 mg.
Intrathecal: 0.2 to 1 mg one time
Intrathecal Continuous: 0.2 mg/24 hours. May be increased up to 20 mg/24 hours.
Intracerebroventricular: 0.25 mg via an Ommaya reservoir.
Rectal: 10 to 30 mg every 4 hours as needed.
Extended-release capsules:
Avinza (R) extended-release capsules and approved generics:
For use only in opioid tolerant patients:
To be taken orally once daily swallowed whole or opened and sprinkled on a small amount of applesauce immediately prior to ingestion.
Maximum dose: 1600 mg orally daily
Kadian (R) extended-release capsules and approved generics:
100 mg and 200 mg for use only in opioid tolerant patients:
To be taken orally 1 to 2 times daily swallowed whole or opened and sprinkled on a small amount of applesauce immediately prior to ingestion.
IM or subcutaneous: 2.5 to 20 mg every 3 to 4 hours as needed
IV: 4 to 15 mg every 3 to 4 hours as needed. Give very slowly over 4 to 5 minutes. Starting doses up to 15 mg every 4 hours have been used. Chest pain: 2 to 4 mg repeat as necessary
Continuous IV: 0.8 to 10 mg/hour. Maintenance dose: 0.8 to 80 mg/hour. Rates up to 440 mg/hour have been used.
IV patient controlled analgesia or subcutaneous patient controlled analgesia: 1 to 2 mg injected 30 minutes after a standard IV dose of 5 to 20 mg. The lockout period is 6 to 15 minutes. The 4 hour limit is 30 mg.
Continuous subcutaneous: 1 mg/hour after a standard dose of 5 to 20 mg
Epidural: 5 mg one time. May give 1 to 2 mg more after one hour to a maximum of 10 mg.
Intrathecal: 0.2 to 1 mg one time
Intrathecal Continuous: 0.2 mg/24 hours. May be increased up to 20 mg/24 hours.
Intracerebroventricular: 0.25 mg via an Ommaya reservoir.
Rectal: 10 to 30 mg every 4 hours as needed.
Usual Pediatric Dose of Morphine for Pain:
Less than or equal to 4 weeks:
Use preservative-free formulation:
Initial: 0.05 mg/kg IM, IV, or subcutaneously every 4 to 8 hours titrating carefully to effect
Maximum dose: 0.1 mg/kg/dose
Continuous Infusion: 0.01 mg/kg/hour continuous IV infusion. Do not exceed infusion rates of 0.015 to 0.02 mg/kg/hour.
Greater than or equal to 1 month but less than 12 years:
Oral: 0.2 to 0.5 mg/kg/dose every 4 to 6 hours (tablets/solution) or 0.3 to 0.6 mg/kg/dose every 12 hours (extended release)
IM,subcutaneous, IV: 0.05 to 0.2 mg/kg/dose (up to 15 mg) every 4 hours as needed.
IV/subcutaneous Continuous: 0.025 to 0.206 mg/kg/hour (sickle cell or cancer pain) or 0.01 to 0.04 mg/kg/hour (postop pain)
Epidural (use preservative-free formulation): 0.025 mg/kg/dose every 6 to 8 hours (postop pain). Maximum per 24 hours: 5 mg.
Greater than or equal to 12 years:
Premedication for anesthesia IV: 3 to 4 mg once, may repeat in 5 minutes if necessary.
Oral: 0.2 to 0.5 mg/kg/dose every 4 to 6 hours (tablets/solution) or 0.3 to 0.6 mg/kg/dose every 12 hours (extended release)
IM,subcutaneous, IV: 0.05 to 0.2 mg/kg/dose (up to 15 mg) every 4 hours as needed
IV/subcutaneous Continuous: 0.025 to 0.206 mg/kg/hour (sickle cell or cancer pain) or 0.01 to 0.04 mg/kg/hour (postop pain)
Epidural (use preservative-free formulation): 0.025 mg/kg/dose every 6 to 8 hours (postop pain). Maximum per 24 hours: 5 mg.
IV patient controlled analgesia: 0.015 mg/kg/dose (postop pain); lockout period of 10 minutes; 4 hour limit of 0.25 mg/kg.
Use preservative-free formulation:
Initial: 0.05 mg/kg IM, IV, or subcutaneously every 4 to 8 hours titrating carefully to effect
Maximum dose: 0.1 mg/kg/dose
Continuous Infusion: 0.01 mg/kg/hour continuous IV infusion. Do not exceed infusion rates of 0.015 to 0.02 mg/kg/hour.
Greater than or equal to 1 month but less than 12 years:
Oral: 0.2 to 0.5 mg/kg/dose every 4 to 6 hours (tablets/solution) or 0.3 to 0.6 mg/kg/dose every 12 hours (extended release)
IM,subcutaneous, IV: 0.05 to 0.2 mg/kg/dose (up to 15 mg) every 4 hours as needed.
IV/subcutaneous Continuous: 0.025 to 0.206 mg/kg/hour (sickle cell or cancer pain) or 0.01 to 0.04 mg/kg/hour (postop pain)
Epidural (use preservative-free formulation): 0.025 mg/kg/dose every 6 to 8 hours (postop pain). Maximum per 24 hours: 5 mg.
Greater than or equal to 12 years:
Premedication for anesthesia IV: 3 to 4 mg once, may repeat in 5 minutes if necessary.
Oral: 0.2 to 0.5 mg/kg/dose every 4 to 6 hours (tablets/solution) or 0.3 to 0.6 mg/kg/dose every 12 hours (extended release)
IM,subcutaneous, IV: 0.05 to 0.2 mg/kg/dose (up to 15 mg) every 4 hours as needed
IV/subcutaneous Continuous: 0.025 to 0.206 mg/kg/hour (sickle cell or cancer pain) or 0.01 to 0.04 mg/kg/hour (postop pain)
Epidural (use preservative-free formulation): 0.025 mg/kg/dose every 6 to 8 hours (postop pain). Maximum per 24 hours: 5 mg.
IV patient controlled analgesia: 0.015 mg/kg/dose (postop pain); lockout period of 10 minutes; 4 hour limit of 0.25 mg/kg.
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